Meet the cutest companions to ever be on screen.

Sometimes the greatest TV and movie actors tend to come on four legs.

Deadpool lovingly holding Dogpool in a scene from "Deadpool & Wolverine"

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Velma, Scooby Doo, Shaggy, Daphne, and Fred stand together in "Scooby Doo, Where Are You?"

Reese Witherspoon and Bruiser Woods sitting in the car in a scene from "Legally Blonde"

Carl and Russell looking at Dug with a collar featuring a red light in a scene from "Up"

Beethoven sitting on the grass with a leash on

Melissa Joan Hart and Salem in Sabrina the Teenage Witch

Wilbur the pig looks up at Charlotte the spider in a barn setting in a scene from "Charlotte's Web"

Brian and Stewie walking down the street in a scene from "Family Guy"

Marley surrounded by a mess of boxes and garage items overturned in a scene from "Marley & Me"

Lupita Nyong'o and Frodo standing by a crowd of people in a scene from "A Quiet Place: Day One"

Lady and Tramp sharing a spaghetti strand at a candlelit dinner

Michelle and Comet in Full House

Kevin Zegers and Buddy on a basketball court in basketball outfits in a scene from "Air Bud"

Lucier smirking around a dirty floor as he sits on the stairs in a scene from "Cinderella"

Babe standing in a grassy field

Charlie Brown gets kicked by Lucy on TV, while Linus is holding his blanket and Snoopy watch

Milo and Otis sitting in a grassy field in a scene from "The Adventures of Milo and Otis"

Marmaduke sticking his head out of a car sunroof next to the beach in a scene from "Marmaduke"

Keanu the cat looking up a person not in the frame

Chance, Shadow, and Sassy standing by grass

Bambi, Thumper, and Flower standing outdoors in a forest setting in a scene from "Bambi"

Two Dalmatians sitting on a carpet in a scene from "101 Dalmatians"

Judy Garland as Dorothy holding Toto in a scene from "The Wizard of Oz"

Lassie walking outside

Grumpy Cat sitting on a cat bed in a scene from "Grumpy Cat's Worst Christmas Ever"

Binx standing on a bunch of leaves in a scene from "Hocus Pocus"